
The world's greatest thief, Carmen Sandiego, leaves cryptic clues while committing near-impossible thefts, such as the space shuttle, the roof of the Taj Mahal, and Paul Revere's horseshoe. On her trail are teen detective duo (and occasionally feuding siblings) Zack and Ivy.
Carmen steals parts of famous artwork to try to create her own personal masterpiece.

Carmen brings items of mysterious origins together in an attempt to contact aliens.

Carmen's dream of landing on the moon inspires her to try and make it come true.

Carmen kidnaps two white lion cubs and sets up her own game preserve for them.

The Player challenges Carmen to a low-tech crime. Carmen accepts the Player's challenge and attempts to steal the Orient Express. Zack and Ivy need some help to solve Carmen's clues and are partnered with a gaucho detective named Armando.

Zack and Ivy are partnered with a Russian detective as they follow Carmen's game-like clues to Hawaii for a life-sized, winner-take-all chess game.

Carmen figures out a way to steal musical talent and transfers it to her two talentless henchwomen. She decides to showcase her accomplishment in a concert inside the stolen Sydney Opera House.

Carmen steals objects that have to do with literature such as Mark Twain's writing desk, Charles Dickens's inkwell, and a jungle ruin like the one that appears in the Jungle Book. They follow Carmen's clues to a remote hideaway in the Swiss Alps where they think Carmen was writing her memoirs. However, she was actually sending the detectives on a wild goose chase while Sara Bellum had tapped into Acme's files and stolen them all.

Carmen pursues objects related to the history of theatre.
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